NZXT CAM detects when other applications are attempting to communicate with your NZXT devices, which can result in errors. If your hardware reports that it cannot be accessed, please close other RGB control programs. Then close CAM and re-open CAM to resolve the issue, in some instances you may need to restart your PC with the offending application disabled from starting up with Windows. This can be done by searching for "Startup Devices" in Windows 10.
If the problem persists, please contact NZXT Customer Support here.