No, it can not as it is software-based LED controller used with CAM to control the RGB strips for the unit. The USB connector that comes with the RGB Gen 1 Controller connects via to your motherboards USB 2.0 header. Which in turn registers the hue+ with windows and also with CAM.
Any further questions about CAM please visit https://cam.nzxt.com/
Any issues regarding the unit please visit support.nzxt.com and submit a request.